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Max Ford, PhD

Toxicologist

Dr. Max Ford serves as a toxicologist with CTEH. His background focuses on principles pertaining to molecular pharmacology, toxicology, virology, and veterinary diagnostics. Initially, Dr. Ford conducted his doctoral dissertation work at the University of Arkansas for Medical Sciences (UAMS) where he researched structure-activity relationships, receptor-mediated signaling processes, and in vivo pharmacological/toxicological effects of novel cannabinoid and opioid ligands. Following the completion of his dissertation at UAMS, he served as an ORISE postdoctoral fellow at the National Center for Toxicological Research where he investigated the molecular and behavioral neurotoxicological effects of anesthetic compounds in both rat and nonhuman primate research models. Before transitioning to CTEH, Dr. Ford served as the virology section supervisor at the Arkansas Veterinary Diagnostic Laboratory where he provided expertise in the field of molecular diagnostics for routine and regulatory diagnostic testing for poultry, livestock, and companion animal cases in Arkansas.

Dr. Ford’s role at CTEH is to provide expertise in environmental toxicology, emergency response, litigation support, and toxicological risk-assessment.

Education

  • Ph.D., Pharmacology and Toxicology, 2017, University of Arkansas for Medical Sciences, Little Rock, AR
  • B.S., Chemistry and Biology, 2012, Ouachita Baptist University, Arkadelphia, AR

Registrations & Certifications

  • OSHA 40-Hour HAZWOPER

(501)801-8500


Publications

  • Ford BM, Tai S, Fantegrossi WE and Prather PL (2017) Synthetic Pot: Not Your Grandfather’s Marijuana. Trends Pharmacol Sci 38:257-276.
  • Ford BM, Franks LN, Tai S, Fantegrossi WE, Stahl EL, Berquist MD, Cabanlong CV, Wilson CD, Penthala NR, Crooks PA and Prather PL (2017) Characterization of structurally novel G protein biased CB1 agonists: Implications for drug development. Pharmacol Res 125:161-177.
  • Ford BM, Franks LN, Radominska-Pandya A, Prather PL (2016) Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development. PLoS One 11(12):e0167240.
  • Ford BM, Cabanlong CV, Tai S, Franks LN, Penthala NR, Crooks PA, Prather PL and Fantegrossi WE (2019) Reduced tolerance and asymmetrical cross-tolerance to effects of indole quinuclidinone analogue PNR-4-20, a G protein biased CB1R agonist in mice: comparisons with Delta9-THC and JWH-018. J Pharmacol Exp Ther.
  • Hutchison RD, Ford BM, Franks LN, Wilson CD, Yarbrough AL, Fujiwara R, Su MK, Fernandez D, James LP, Moran JH, Patton AL, Fantegrossi WE, Radominska-Pandya A, and Prather PL (2018) Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Delta(9)-THC. Front Pharmacol 9: 1084.
  • Franks LN, Ford BM, Fujiwara T, Zhao H, and Prather PL (2018) Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity. Front Pharmacol 7:503.
  • Franks LN, Ford BM, Fujiwara T, Zhao H, and Prather PL (2016) The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects. Toxicol Appl Pharmacol 353: 31-42.
  • Yadlapalli JS, Ford BM, Ketkar A, Wan A, Penthala NR, Eoff RL, Prather PL, Dobretsov M and Crooks PA (2016) Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors. Pharmacol Res 113:335-347.
  • Franks LN, Ford BM, Madadi NR, Penthala NR, Crooks PA and Prather PL (2014) Characterization of the intrinsic activity for a novel class of cannabinoid receptor ligands: Indole quinuclidine analogs. Eur J Pharmacol 737:140-148.
  • Madadi NR, Penthala NR, Brents LK, Ford BM, Prather PL and Crooks PA (2013) Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. Bioorg Med Chem Lett 23:2019-2021.
  • Prather PL, FrancisDevaraj F, Dates CR, Greer AK, Bratton SM, Ford BM, Franks LN and Radominska-Pandya A (2013) CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen. Biochem Biophys Res Commun 441:339-343.
  • Vasiljevik T, Franks LN, Ford BM, Douglas JT, Prather PL, Fantegrossi WE and Prisinzano TE (2013) Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse. J Med Chem 56:4537-4550.

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